PRP for a Thin Uterine Lining: How Intrauterine PRP Supports Your Fertility Plan
By Dr. Laura Clevenger, ND, Origins Integrative Health, Portland
If you're reading about PRP for a thin uterine lining, you've likely been working hard toward a pregnancy. Maybe your lining hasn't thickened the way you hoped. Maybe a transfer didn't take, and you're looking for something more you can do.
Intrauterine PRP is a promising option for supporting the uterine lining, and it's something we offer right here in SE Portland. This article explains what it is, who it may help, and what to expect when you come see us.
What intrauterine PRP is
PRP stands for platelet-rich plasma. It's made from a small sample of your own blood, concentrated so it's rich in platelets. Platelets carry growth factors, the natural signals your body uses to repair and renew tissue.
With intrauterine PRP, that concentrate is gently placed inside the uterus to nourish the lining where an embryo implants. Because it comes from your own body, nothing foreign is added.
At Origins, I offer low-volume, high-concentration intrauterine PRP infusions. Every PRP treatment here is prepared with an FDA-approved device, using only fresh plasma, never frozen.
For a deeper look at the science, read my article What Is Intrauterine PRP and Can It Help You Get Pregnant?
Who it may help
Intrauterine PRP is most often considered for people who have:
- A thin uterine lining that hasn't responded the way they hoped to estrogen support
- Had transfers that didn't implant, even with good-quality embryos
- Scarring inside the uterus (Asherman's syndrome), as support while the lining regrows after treatment
- Unexplained infertility with questions about the lining
It can be part of IVF and embryo transfer cycles, IUI, or trying naturally. Your plan is built around where you are right now.
What the research shows
Research on intrauterine PRP is growing, and the findings for thin linings are encouraging. A 2024 review of 8 randomized trials included 678 women. Those who received PRP had a thicker lining, higher pregnancy rates and higher live birth rates than those who didn't. The authors concluded that intrauterine PRP may be an effective and safe treatment for thin lining.
It's a newer therapy, and research continues to build. We'll walk through what it means for your situation at your consultation, so you can make the choice that feels right for you.
Working alongside your fertility team
If you're already working with a fertility clinic or IVF team, intrauterine PRP fits into the plan you have. We coordinate timing with your cycle and your transfer, and we're happy to work alongside your reproductive endocrinologist or OB-GYN.
Bring your records and any notes from your fertility team to your first visit. That helps us build a plan that works with everything you're already doing.
What a visit is like
Your care starts with a consultation. We'll talk through your history, your goals and where you are in your fertility plan. Then we'll decide together whether intrauterine PRP is a good fit.
On the day of your procedure, it's quick and done right in our office. A small blood draw comes first, then your PRP is prepared and gently placed. No sedation is needed, and most people go back to their usual day afterward. You'll leave with clear instructions for the days ahead.
PRP can also be one part of broader fertility support at Origins, alongside acupuncture, naturopathic medicine and bodywork. See everything we offer on our fertility page, or get a quick overview on our intrauterine PRP in Portland page.
Insurance and payment
Intrauterine PRP isn't covered by insurance. Your full plan, including the number of treatments that makes sense for you, is discussed at your consultation before anything is scheduled. Call us for pricing.
Who performs intrauterine PRP at Origins
I'm a naturopathic doctor focused on fertility for people of all genders. I was also one of the first providers to bring intrauterine PRP to Oregon. I'm an inclusive, LGBTQ+ affirming provider, and I'm glad to support every path to parenthood.
Frequently asked questions
Does intrauterine PRP hurt?
Most people find it very manageable, often similar to a Pap smear. The procedure itself only takes a few minutes, and we make sure you're comfortable the whole time.
Can I have PRP while working with an IVF clinic?
Yes. We coordinate timing with your cycle and your transfer, and we're happy to work alongside your fertility team.
Is intrauterine PRP covered by insurance?
It isn't covered by insurance. We go over your plan at your consultation. Call us for pricing.
How many treatments will I need?
It depends on your history and your goals. We'll recommend a plan that fits your situation at your consultation.
When you're ready
Every path to parenthood is personal, and you don't have to figure out the next step alone. If you'd like to talk about whether intrauterine PRP is right for you, contact us or call (503) 314-2176 to set up a consultation. We're at 1421 SE Ankeny St in Southeast Portland.